Accurately positioning functional residues with robotics-inspired computational protein design
C. Krivacic, K. Kundert, X. Pan, R. A. Pache, L. Liu, S. O Conchuir, J. R. Jeliazkov, J. J. Gray, M. C. Thompson, J. S. Fraser, T. Kortemme
This paper introduces two computational methods for accurately positioning functional residues in proteins and validates them by redesigning enzyme active sites.
bioRxiv · Jul 2, 2021 · PreprintBioengineering