Author

K. L. West

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. G. West· 1 shared A. K. Byrd· 1 shared B. H. May· 1 shared B. Kader· 1 shared B. Osei· 1 shared C. M. Stiefel· 1 shared E. Bergstrom· 1 shared E. J. Enemark· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. G. West

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Author profile →

2 papers

Recent·Most cited

Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB

B. Osei, B. H. May, C. M. Stiefel, K. L. West, M. K. Zafar, M. D. Thomoson, E. Bergstrom, J. W. Leung, E. J. Enemark, A. K. Byrd

The paper identifies a rare SNP in the HELB gene that disrupts its interaction with RPA and affects age at natural menopause through impaired DNA repair function.

bioRxiv · Feb 27, 2024Biochemistry

EZH2 inhibition in glioblastoma stem cells increases the expression of neuronal genes and the neuronal developmental regulators ZIC2, ZNF423 and MAFB

B. Kader, R. DiStefano, K. L. West, A. G. West

This study shows that EZH2 inhibition in GBM stem cells increases neuronal gene expression and the expression of ZIC2, ZNF423, and MAFB, suggesting a role for EZH2 in suppressing neurogenesis in GBM.

bioRxiv · Nov 22, 2021 · PreprintCancer Biology