Author

E. Bergstrom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

J. Kim· 2 shared A. Boot· 1 shared A. Di Genova· 1 shared A. Gilg Soit Ilg· 1 shared A. Gonzalez-Perez· 1 shared A. K. Byrd· 1 shared A. Khandekar· 1 shared A. Moreno-Ocampo· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

J. Kim

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Author profile →

4 papers

Recent·Most cited

Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB

B. Osei, B. H. May, C. M. Stiefel, K. L. West, M. K. Zafar, M. D. Thomoson, E. Bergstrom, J. W. Leung, E. J. Enemark, A. K. Byrd

The paper identifies a rare SNP in the HELB gene that disrupts its interaction with RPA and affects age at natural menopause through impaired DNA repair function.

bioRxiv · Feb 27, 2024Biochemistry

Formation of sulfoquinovosyl diacylglycerol by acylation of sulfoquinovosyl glycerol

J. Y. Cuevas-Rivas, D. Rodriguez-Terrones, N. Gonzalez-Silva, A. Moreno-Ocampo, G. Guerrero, E. Bergstrom, J. E. Thomas-Oates, O. Geiger, I. M. Lopez-Lara

This paper identifies SqdA as an acyltransferase that converts sulfoquinovosyl glycerol to sulfoquinovosyl diacylglycerol in bacteria, and shows its enzymatic activity and evolutionary distribution.

bioRxiv · Aug 18, 2022 · PreprintMicrobiology

Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses

L. Mangiante, N. Alcala, A. Di Genova, A. Sexton-Oates, A. Gonzalez-Perez, A. Khandekar, E. Bergstrom, J. Kim, C. Giacobi, N. Le-Stang, S. Boyault, C. Cuenin, S. Tabone-Eglinger, F. Damiola, C. Voegele, , Meyer

This study identifies four sources of heterogeneity in MPM using multi-omic factor analysis, showing how genomic events shape molecular profiles and clinical behavior.

bioRxiv · Sep 27, 2021Cancer Biology

The Repertoire of Mutational Signatures in Human Cancer

L. Alexandrov, J. Kim, N. J. Haradhvala, M. N. Huang, A. W. T. Ng, Y. Wu, A. Boot, K. R. Covington, D. A. Gordenin, E. Bergstrom, S. M. A. Islam, N. Lopez-Bigas, L. J. Klimczak, J. R. McPherson, S. Morganella, , M. R. Stratton

The paper characterizes 49 mutational signatures in human cancer using a large dataset of somatic mutations, revealing associations with exposures and DNA repair mechanisms and identifying signatures of unknown origin.

bioRxiv · Jul 3, 2019Cancer Biology