Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks
M. Hernandez Mesa, J. van der Brink, W. E. Louch, K. McCabe, P. Rangamani
The paper uses computational modeling to show that RyR cluster geometry and phosphorylation patterns affect Ca2+ spark dynamics in heart failure.
bioRxiv · Oct 19, 2021Biophysics