Author

K. Sachsenmeier

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Swanton· 1 shared D. Biswas· 1 shared D. C. Hancock· 1 shared G. Kelly· 1 shared J. Downward· 1 shared M. Marani· 1 shared P. East· 1 shared S. de Carne Trecesson· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

C. Swanton

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1 paper

Recent·Most cited

Oncogenic RAS activity predicts response to chemotherapy and outcome in lung adenocarcinoma

P. East, G. Kelly, D. Biswas, M. Marani, D. C. Hancock, T. Creasy, K. Sachsenmeier, C. Swanton, S. de Carne Trecesson, J. Downward

This study develops a transcriptional signature to measure RAS pathway activity in lung adenocarcinoma, showing it better predicts chemotherapy response and prognosis than KRAS mutation status.

bioRxiv · Apr 2, 2021Cancer Biology