Myofibrillar Structural Variability Underlies Contractile Function in Stem Cell-Derived Cardiomyocytes
K. Ufford, S. Friedline, Z. Tong, V. T. Tang, A. S. Dobbs, Y.-C. Tsan, S. L. Bielas, A. P. Liu, A. S. Helms
This study shows myofibrillar structure variability in iPSC-derived cardiomyocytes affects contractile function and should be considered in disease modeling and drug testing.
bioRxiv · Oct 13, 2020Cell Biology