Author

Kai Mao

Harvard University

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Genetics· 1

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Organism:C. elegans· 1 Approach:experimental assay· 1

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Gary RuvkuniD· 1 shared Peter C. Breen· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperGenetics

Gary RuvkunORCID

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Recent·Most cited

Induction of RNA interference by C. elegans mitochondrial dysfunction via the DRH-1/RIG-I homologue RNA helicase and the EOL-1/RNA decapping enzyme

Kai Mao, Peter C. Breen, Gary Ruvkun

This study shows that mitochondrial dysfunction in C. elegans activates RNAi through a pathway similar to the mammalian RIG-I response, involving DRH-1 and EOL-1, and contributes to increased longevity.

bioRxiv · Jun 5, 2020 · PreprintGenetics