Pick Your Poison: Tetrodotoxin Variants Give Pacific Newts a Potential Leg Up in the Coevolutionary Arms Race with Resistant Garter Snake Predators
Kait Malewicz, Kelly E. Robinson, Anne M. Brown, Christopher S. Jeffrey, Casey S. Philbin, Joel W. McGlothlin, Justin A. Lemkul, Chris R. Feldman
This study identifies diverse tetrodotoxin analogs in Pacific newts and shows some are more effective against resistant garter snake sodium channels.
bioRxiv · May 29, 2026 · PreprintEvolutionary Biology