Author

Kari C. Close

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:Drosophila· 3 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Organism:non-human primate· 1

Frequent Co-Authors

Gudrun IhrkeiD· 3 shared Alyson PetruncioiD· 2 shared Christina P. Christoforou· 2 shared Geoffrey Wilson MeissneriD· 2 shared Gerald M. RubiniD· 2 shared Heather DionneiD· 2 shared Michael-John DolaniD· 2 shared Yisheng HeiD· 2 shared

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2018-2025 · peak 2/yr

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10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Gudrun IhrkeORCID

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4 papers

Recent·Most cited

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

Virginia M. S. Ruetten, Weihao Zheng, Igor Siwanowicz, Brett D. Mensh, Mark Eddison, Amy Hu, Yunfeng Chi, Andrew L. Lemire, Caiying Guo, Mykola Kadobianskyi, Marc Renz, Sara Lelek-Greskovic, Yisheng He, Kari C. Close, Gudrun Ihrke, , Misha B. Ahrens

The paper introduces WHOLISTIC, a method to image cellular activity across all organs of a vertebrate, revealing body-wide circuits and responses to stimuli.

bioRxiv · Aug 20, 2025 · PreprintNeuroscience

A split-GAL4 driver line resource for Drosophila neuron types

Geoffrey Wilson Meissner, Allison Vannan, Jennifer Jeter, Kari C. Close, Gina M DePasquale, Zachary Dorman, Kaitlyn Forster, Jaye Anne Beringer, Theresa V Gibney, Joanna H Hausenfluck, Yisheng He, Kristin Henderson, Lauren Johnson, Rebecca M. Johnston, Gudrun Ihrke, , FlyLight Project Team

The paper describes a collection of split-GAL4 driver lines for targeting specific neuron types in Drosophila, enabling functional and molecular studies.

eLife · Jan 24, 2025Peer-reviewedNeuroscience

Hacking brain development to test models of sensory coding

Maria Ahmed, Adithya E. Rajagopalan, Yijie Pan, Ye Li, Donnell L. Williams, Erik A. Pedersen, Manav Thakral, Angelica Previero, Kari C. Close, Christina P. Christoforou, Dawen Cai, Glenn C Turner, E. Josephine Clowney

The paper modifies circuit parameters in Drosophila mushroom bodies to assess how changes affect odor selectivity and discrimination.

bioRxiv · Jan 25, 2023 · PreprintNeuroscience

Neurogenetic dissection of the Drosophila innate olfactory processing center

Michael-John Dolan, Shahar Frechter, Alexander Shakeel Bates, Chuntao Dan, Paavo Huoviala, Ruairí J.V. Roberts, Philipp Schlegel, Serene Dhawan, Remy Tabano, Heather Dionne, Christina P. Christoforou, Kari C. Close, Ben Sutcliffe, Bianca Giuliani, Feng Li, , Gregory S.X.E. Jefferis

The paper generates split-GAL4 driver lines to map and functionally characterize 82 cell types in the Drosophila lateral horn, revealing connectivity with mushroom bodies and identifying cell types that influence behavior.

bioRxiv · Sep 12, 2018 · PreprintNeuroscience