Phage-Inducible Chromosomal Jumbo Islands (PICJIs) spreading antimicrobial resistance, host-adaptation factors and defense systems, a novel satellite family of nucleus-forming Chimalliviridae
Aurore Rossignol, Karine Praud, Mélodie Roxane Alexandre, Myriam Mikhayel, Isabelle Foubert, Pierre-Ivan Raynal, Laetitia Fabre, Sebastien Olivier Leclercq, François-Xavier Weill, Dolla Karam Sarkis, Benoît Doublet
The paper identifies PICJIs as large mobile genetic elements in E. coli and Salmonella that spread antimicrobial resistance and defense systems via a specific bacteriophage.
bioRxiv · Nov 4, 2026 · PreprintMicrobiology