Deficiency of p38&α-MAPK in myeloid cells ameliorates symptoms and pathology of APP-transgenic AD mice
Qinghua Luo, Laura Schnöder, Wenlin Hao, Kathrin Litzenburger, Yann Decker, Inge Tomic, Michael Dieter Menger, Klaus C Fassbender, Yang Liu
This study shows that deleting p38-MAPK in myeloid cells reduces Aβ levels and improves cognitive function in APP-transgenic AD mice.
bioRxiv · Oct 18, 2021 · PreprintNeuroscience