Ubp3 mediates dynamic deubiquitination of mitochondria upon induction of mitophagy
Kai Voeltzke, Lars Bostelmann-Arp, Christina Behrendt, Mareike Breuer, Simon Vesper, Katja Bendrin, Lenka Geerkens, Melissa Vázquez-Carrada, Lasse van Wijlick, Ursula N. Fleig, Michael Feldbrügge, Lutz Schmitt, Andreas S. Reichert
This study shows Ubp3 dynamically regulates mitochondrial ubiquitination during mitophagy, revealing its role in ubiquitin storage and release as a stress response mechanism.
bioRxiv · Sep 18, 2026 · PreprintCell Biology