Monocyte-derived transcriptome signature indicates antibody-dependent cellular 1 phagocytosis as the primary mechanism of vaccine-induced protection against HIV-1
Shida Shangguan, Philip K. Ehrenberg, Aviva Geretz, Lauren K. Yum, Gautam Kundu, Kelly May, Slim Fourati, Krystelle Nganou‐Makamdop, LaTonya D. Williams, Sheetal S. Sawant, Éric Lewitus, Punnee Pitisuttithum, Sorachai Nitayaphan, Suwat Chariyalertsak, Supachai Rerks‐Ngarm, , Rasmi Thomas
The paper identifies a monocyte-derived transcriptome signature linked to antibody-dependent cellular phagocytosis as a correlate of vaccine-induced protection against HIV-1 in clinical trials.
eLife · Sep 17, 2021Peer-reviewedSystems Biology