Boltz-1: Democratizing Biomolecular Interaction Modeling
Jeremy Wohlwend, Gabriele Corso, Saro Passaro, Noah Getz, Mateo Reveiz, Ken Leidal, Wojtek Swiderski, Liam Atkinson, Tally Portnoi, Itamar Chinn, Jacob Silterra, Tommi Jaakkola, Regina Barzilay
Open-source Boltz-1 predicts biomolecular complex structures comparably to AlphaFold3 and Chai-1 on CASP15 and recent PDB targets; Boltz-steering lets 97% of test-set poses pass physical checks.
bioRxiv · Nov 19, 2024 · PreprintBiophysics✦ In-depth digest