Stressed β-cells contribute to loss of peri-islet extracellular matrix in type 1 diabetes
Chelsea G. Johansen, Kenedee Lam, Nikki L. Farnsworth
This study shows stressed β-cells increase MMP-3, leading to loss of peri-islet ECM in T1D, suggesting MMP-3 inhibition could prevent islet death.
Frontiers in Endocrinology · Oct 10, 2025Peer-reviewedCell Biology