Author

Kersten Heyer

Technical University of Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adrian StraubiD· 2 shared Benjamin SchubertiD· 2 shared Dirk Hans BuschiD· 2 shared Felix DrostiD· 2 shared Kilian SchoberiD· 2 shared Abagail Delahoussaye· 1 shared Anton Mühlbauer· 1 shared Bernd BischliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Adrian StraubORCID

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2 papers

Recent·Most cited

Germline-encoded V(D)J gene usage does not impose strict constraints on the epitope-specificity of T cell receptors

Adrian Straub, Yang An, Felix Drost, Kersten Heyer, Zahra Abedi, Monika Hammel, Abagail Delahoussaye, Sabrina Wagner, Anton Mühlbauer, Julian Hönninger, Jack Barton, Karl Moukarzel, Linda Warmuth, Sarah Braun, Laura Valentiner, , Dirk Hans Busch

The study identifies over 27,000 unique epitope-reactive TCRs from immunized mice, showing that TCR diversity is not constrained by germline VJ combinations but by combinatorial pairing of segments and CDR3 sequences.

bioRxiv · Aug 20, 2026 · PreprintImmunology

Predicting T Cell Receptor Functionality against Mutant Epitopes

Felix Drost, Emilio Dorigatti, Adrian Straub, Philipp Hilgendorf, Karolin I. Wagner, Kersten Heyer, Marta López Montes, Bernd Bischl, Dirk Hans Busch, Kilian Schober, Benjamin Schubert

P-TEAM predicts the effect of epitope mutations on T cell functionality using a Random Forest model trained on murine and human TCR-epitope interactions.

Cell Genomics · Aug 15, 2024Peer-reviewedBioinformatics