Reducing Supply Chain Dependencies for Viral Genomic Surveillance: Get by with a Little HELP from Commercial Enzymes already in your Lab Freezer
Ganna Kovalenko, Myra D.T. Hosmillo, Chris Kent, Kess Rowe, Andrew Rambaut, Nicholas James Loman, Joshua Quick, Ian Goodfellow
The paper develops ARTIC HELP, an open-source alternative to ARTIC nanopore sequencing protocols using commercial enzymes, achieving comparable genome coverage for SARS-CoV-2 and Norovirus GII with reduced supply chain dependencies.
Wellcome Open Research · Oct 1, 2025Peer-reviewedGenomics