Stress-Induced Alteration of Small Extracellular Vesicles Drives Amyloid-Beta Sequestration and Exacerbates Alzheimer's Disease Pathogenesis
Sadaqa Zehra, Sanskriti Rai, Komal Rani, Saumitra Dey Choudhury, Himanshu Rai, Suchismita Bhowmik, Nitin Mohan, Anu Gupta, Prasun Chatterjee, Thota Jagadeshwar Reddy, Neerja Rani, Gyan Prakash Modi, Fredrik Nikolajeff, Saroj Kumar
This study shows stress-induced changes in small extracellular vesicles (sEVs) enhance their binding to amyloid-beta aggregates, promoting plaque formation and disease progression in Alzheimer's.
Alzheimer s Research & Therapy · Apr 11, 2026Peer-reviewedNeuroscience