Author

Kottapalli Srividya

Central Drug Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aamir NaziriD· 2 shared Aamir NaziriD· 1 shared Aayushi Agrawal· 1 shared Anil KouliD· 1 shared Ankur GautamiD· 1 shared Arpit GuptaiD· 1 shared Arpit MehrotraiD· 1 shared Arunabh SarkariD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetics

Aamir NazirORCID

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4 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 22, 2025

T13F2.2 of C. elegans is Critical for Chromatin Organization, Autophagy, and Longevity

Rohil Hameed, Sweta Sikder, Aayushi Agrawal…·Tapas Kumar Kundu

This study identifies T13F2.2 as a critical gene in C. elegans that affects chromatin structure, autophagy, and lifespan through RNAi depletion and transcriptomic analysis.

DOI 10.1101/2025.09.22.677762

C. elegansexperimental assay

Molecular BiologybioRxivPreprintJan 18, 2024

Changes in microglia chromatin accessibility in aged female mice.

Victor A. Ansere, Kyla B. Tooley, Kottapalli Srividya…·Willard M. Freeman

This study identifies age-related changes in chromatin accessibility in female microglia, showing more gains than losses in accessibility, enriched in immune-related genes and intergenic regions.

DOI 10.1101/2024.01.18.575944

mouseATAC-seq

NeurosciencebioRxivPreprintJun 24, 2022

Penetratin inhibits α-synuclein fibrillation and improves locomotor functions in mice model of Parkinsons disease

Arpit Gupta, Priyanka Singh, Arpit Mehrotra…·Deepak Sharma

This study identifies penetratin as an inhibitor of α-synuclein aggregation and shows it improves locomotor function in Parkinson's disease mouse models.

5 citations

mouseexperimental assay

NeurosciencebioRxivPreprintJul 30, 2020

Targeted downregulation of estradiol binding Na+/H+ exchanger nhx-2, mimics calorie restriction, extends reproductive longevity and ameliorates effects associated with alpha synuclein aggregation in C. elegans

Shikha Shukla, Lalit Kumar, Arunabh Sarkar…·Aamir Nazir

This study identifies nhx-2 as a modulator that extends reproductive longevity and ameliorates alpha-synuclein aggregation effects in C. elegans by mimicking dietary restriction.

4 citations

C. elegansstatistical model