In Step, the sole Drosophila TENT5 poly(A) polymerase, is required for spermatid elongation and individualization
Abdulqater Al-Nouman, Kyle Helms, Brook L. Falk, Julie A. Brill, Jennifer Curtiss
This study identifies the Drosophila TENT5 poly(A) polymerase, Isep, as essential for spermatid elongation and individualization, with its function independent of poly(A) polymerase activity.
bioRxiv · Oct 26, 2026 · PreprintDevelopmental Biology