Author

Kyoko Otsuka

Kyushu University Beppu Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ayako Kuwahara· 2 shared Daisuke OryojiiD· 2 shared Goro Doi· 2 shared Hiroaki NiiroiD· 2 shared Hiroki MitomaiD· 2 shared Koichi AkashiiD· 2 shared Masahiro AyanoiD· 2 shared Naoya NishimuraiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Ayako Kuwahara

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Layer-to-cell-class correspondence is gene-specific for pyroptosis-related transcription in human skin

Daisuke Oryoji, Goro Doi, Sho Fujimoto, Naoya Nishimura, Kyoko Otsuka, Ayako Kuwahara, Masahiro Ayano, Yasutaka Kimoto, Koichi Akashi, Hiroaki Niiro, Hiroki Mitoma

Epidermal NLRP1, PYCARD and CASP4 versus dermal GSDMD polarity in systemic sclerosis skin is reproduced by same-donor cell-class pseudobulk for PYCARD and GSDMD, but rarely NLRP1.

bioRxiv · Sep 23, 2026 · PreprintImmunology✦ In-depth digest

GSDMD transcript levels are higher in endothelial than cardiomyocyte compartments across three human heart cohorts

Daisuke Oryoji, Goro Doi, Sho Fujimoto, Naoya Nishimura, Kyoko Otsuka, Ayako Kuwahara, Masahiro Ayano, Yasutaka Kimoto, Koichi Akashi, Hiroaki Niiro, Hiroki Mitoma

The paper compares GSDMD transcript levels between endothelial and cardiomyocyte compartments across three human heart cohorts, finding consistently higher levels in endothelial cells.

bioRxiv · Sep 10, 2026 · PreprintCell Biology