Author

L. Baciou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

T. Bizouarn· 2 shared A. Deniset-Besseau· 1 shared A. Taly· 1 shared B. A. Fas· 1 shared H. Santuz· 1 shared H. Valenta· 1 shared M. Erard· 1 shared O. Nüsse· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

T. Bizouarn

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Author profile →

2 papers

Recent·Most cited

Combining computational biology and experimental knowledge to draw a structural profile of the active membrane-assembled NADPH oxidase complex

S. Z. Aimeur, B. A. Fas, X. Serfaty, H. Santuz, S. Sacquin-Mora, T. Bizouarn, A. Taly, L. BACIOU

The paper models the structure of the active NOX2 complex using AlphaFold2 and experimental data, revealing the role of disordered regions in subunit assembly.

bioRxiv · Feb 19, 2024 · PreprintBiochemistry

Consequences of the constitutive NOX2 activity in living cells: cytosol acidification, apoptosis, and localized lipid peroxidation

H. Valenta, S. Dupre-Crochet, T. Bizouarn, L. Baciou, O. Nüsse, A. Deniset-Besseau, M. Erard

This study uses a chimeric protein to induce continuous NOX2 activity in cells and shows it causes cytosolic acidification, apoptosis, and localized lipid peroxidation.

bioRxiv · Feb 23, 2021Biophysics