Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates
Z. Baker, M. Schumer, Y. Haba, L. Bashkirova, C. Holland, G. G. Rosenthal, M. Przeworski
The paper identifies PRDM9 orthologs across 225 vertebrate species and finds repeated losses of PRDM9-directed recombination despite its conservation, linking complete orthologs to rapid evolution of binding affinity.
eLife · Jun 6, 2017Peer-reviewedEvolutionary Biology