Evaluation of 1, 4, 7-Triazacyclononane (TACN) as a potential Metallo-B-Lactamase inhibitor in Enterobacteriaceae: Restoring the Activity of B-lactams
A. M. Somboro, D. G. Amoako, J. Osei Sekyere, H. M. Kumalo, R. Khan, L. Bester, S. Essack
This study evaluates TACN as a potential MBL inhibitor, showing it restores carbapenem activity against CREs and demonstrates efficient inhibition with low cytotoxicity.
bioRxiv · Sep 6, 2018Microbiology