R. Khan

Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice

This study evaluates two compounds that reduce triglyceride content in Mtb-infected macrophages but finds they do not reduce bacterial burden or inflammation in infected mice.

Exploration of the intricacies of low light-induced changes in cigar tobacco leaf anticlinal growth: A holistic approach from anatomical and hormonal levels to gene expression

This study examines how low light affects cigar tobacco leaf morphology, growth rates, and gene expression, revealing hormonal and cellular changes in leaf structure.

Polymer biodegradation by Halanaerobium promotes reservoir souring during hydraulic fracturing.

The paper investigates how Halanaerobium metabolizes guar gum in produced water from hydraulic fracturing, showing that polymer biodegradation at 30°C generates fermentation intermediates that contribute to reservoir souring when introduced into subsurface environments at 60°C.

Cryptococcosis, tuberculosis, and a kidney cancer fail to fit the atherosclerosis paradigm for foam cell lipid content

The paper investigates lipid accumulation in foam cells across different diseases and finds that lipid content varies by disease and microenvironment.

DBDA matrix increases ion abundance of fatty acids and sulfatides in MALDI-TOF and mass spectrometry imaging studies

The paper demonstrates that DBDA matrix enhances ionization of fatty acids and sulfatides in MALDI-TOF mass spectrometry imaging of mouse brain tissue.

Colon Innervating TRPA1 Positive Nociceptors Influence Mucosal Health In Mice

This study shows that TRPA1+ve nociceptors are essential for maintaining colonic mucus layer integrity and gut health in mice.

Chromosome size affects sequence divergence between species through the interplay of recombination and selection

The paper investigates how chromosome size influences sequence divergence between species by analyzing empirical data and evolutionary simulations across mammalian clades.

Agricultural production and CO2 emissions causes in the developing and developed countries: New insights from quantile regression and decomposition analysis

This study uses quantile regression and decomposition analysis to examine the heterogeneous determinants of CO2 emissions in developing and developed countries, finding agriculture's mixed impact on emissions.

New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancer

This study identifies FDA-approved drugs that enhance radioiodide uptake through non-canonical NIS processing pathways, revealing new therapeutic strategies for thyroid cancer.

Limited evidence for parallel evolution among desert adapted Peromyscus deer mice

The paper examines genome evolution in desert-adapted Peromyscus mice and finds limited evidence for parallel evolution, suggesting divergent molecular mechanisms of adaptation.

Prognostic significance of Substance P/ Neurokinin 1 receptor and its association with hormonal receptors in breast carcinoma

The paper evaluates Substance P and NK-1R expression in breast carcinoma and finds significant association with tumor grade, suggesting potential as a biomarker and therapeutic target.

Conserved pheromone production, response and degradation by Streptococcus mutans

This study investigates the conservation of pheromone production, response, and degradation in Streptococcus mutans isolates, finding that XIP induces transformation and CSP is degraded proteolytically across strains.

Mouse IgG2a antibodies specific for the commensal Streptococcus mitis show stronger cross-reactivity with Streptococcus pneumoniae than IgG1 antibodies

To examine environmental pollution by economic growth and their impact in an environmental Kuznets curve (EKC) among developed and developing countries.

This study examines the environmental Kuznets curve hypothesis to analyze the relationship between economic growth and pollution across developed and developing countries using panel data and econometric methods.

Evaluation of 1, 4, 7-Triazacyclononane (TACN) as a potential Metallo-B-Lactamase inhibitor in Enterobacteriaceae: Restoring the Activity of B-lactams

This study evaluates TACN as a potential MBL inhibitor, showing it restores carbapenem activity against CREs and demonstrates efficient inhibition with low cytotoxicity.

In Vitro Potentiation of Carbapenems with Tannic Acid Against Carbapenemase Producing Enterobacteriaceae: Exploring Natural Products as Potential Carbapenemase Inhibitors

This study shows tannic acid can reduce carbapenem resistance in Enterobacteriaceae by inhibiting carbapenemases, with stronger effects on metallo-β-lactamases than serine-β-lactamases.