Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis.
M. K. Ried, R. Wild, J. Zhu, L. Broger, R. K. Harmel, L. A. Hothorn, D. Fiedler, M. Hothorn
The paper shows that InsP8 binds to SPX domains, altering PHR transcription factors' oligomeric state and DNA binding, thus regulating phosphate homeostasis in plants.
bioRxiv · Dec 13, 2019Plant Biology