Author

L. Chemes

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

G. Muller· 1 shared J. Lewis· 1 shared L. Alvarez· 1 shared P. Sehr· 1 shared S. Fernandez· 1 shared S. Ludtke· 1 shared S. Putta· 1 shared S. Rubin· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

G. Muller

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1 paper

Recent·Most cited

Structural basis for tunable affinity and specificity of LxCxEdependentprotein interactions with the retinoblastoma protein family

S. Putta, L. Alvarez, S. Ludtke, P. Sehr, G. Muller, S. Fernandez, S. Tripathi, J. Lewis, T. Gibson, L. Chemes, S. Rubin

This study presents crystal structures of the p107 pocket domain bound to LxCxE peptides, revealing structural determinants that explain differences in binding affinity between viral and cellular proteins.

bioRxiv · Jun 10, 2022Biochemistry