Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069
M. Saye, L. Gauna, E. Valera-Vera, C. Reigada, M. Miranda, C. A. Pereira
This paper identifies crystal violet structural analogues with anti-Trypanosoma cruzi activity by inhibiting the proline transporter TcAAAP069 and shows synergistic effects with benznidazole.
bioRxiv · May 21, 2019Microbiology