Cancer BiologybioRxiv
An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression
R. Sordella, D. Pal, P. Safaric Tepes…·G. Hannon
The paper identifies an epigenetic mechanism regulating AXL-positive/Erlotinib-resistant cells through miR-335 expression, suggesting combinatorial therapies for EGFR-mutated NSCLC.
DOI 10.7554/elife.66109