Author

L. Guy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Research Focus:phylogenetics / evolution· 2 Organism:Arabidopsis· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. B. Moreno· 2 shared A. Jex· 1 shared A. M. Floriano· 1 shared A. M. Palomar· 1 shared A. Vijay· 1 shared B. Kacar· 1 shared B. L. Makepeace· 1 shared C. Ginevra· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

A. B. Moreno

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer

A. B. Moreno, V. Ek, J. Eriksson, M. E. Sellin, L. Guy

This paper introduces a cost-effective and efficient transfection method for Acanthamoeba castellanii using polyethylenimines, achieving up to 100-fold higher efficiency than existing protocols.

bioRxiv · Dec 1, 2022 · PreprintMicrobiology

Rapid, in-patient adaptations of Legionella pneumophila to the human host

D. Leenheer, A. B. Moreno, S. Murray, S. Jarraud, C. Ginevra, L. Guy

This study identifies two genes with mutations in multiple human infections of Legionella pneumophila, suggesting they may be adaptations to the human host, though the bacteria are not well adapted overall.

bioRxiv · May 23, 2022Microbiology

The origin and evolution of mitochondrial tropism in Midichloria bacteria

A. M. Floriano, G. Batisti Biffignandi, M. Castelli, E. Olivieri, E. Clementi, F. Comandatore, L. Rinaldi, M. Opara, O. Plantard, A. M. Palomar, V. Noel, A. Vijay, N. Lo, B. L. Makepeace, O. Duron, , D. Sassera

This study analyzes mitochondrial tropism in three additional Midichloria species and sequences nine novel genomes, revealing non-monophyletic patterns and genomic signatures associated with mitochondrial colonization.

bioRxiv · May 16, 2022 · PreprintEvolutionary Biology

Host-adaptation in Legionellales is 2.4 Gya, coincident with eukaryogenesis

E. Hugoson, T. Ammunet, L. Guy

The paper analyzes 35 Legionellales genomes to show host-adaptation events occurred 2.4 billion years ago, predating eukaryotic origins.

bioRxiv · Feb 27, 2020Evolutionary Biology

Resurrecting ancestral genes in bacteria to interpret ancient biosignatures

B. Kacar, L. Guy, E. Smith, J. A. Baross

This paper resurrects ancestral bacterial carbonic anhydrase proteins to link ancient environmental conditions with biosignatures preserved in the geological record.

bioRxiv · Aug 31, 2017Evolutionary Biology