A. Jex

Machine learning driven image segmentation and shape clustering of algal microscopic images obtained from various water types

This study applies FastSAM for automated algal cell segmentation and clustering in water samples, showing high accuracy for single cells and varying clustering performance.

The origin and evolution of mitochondrial tropism in Midichloria bacteria

This study analyzes mitochondrial tropism in three additional Midichloria species and sequences nine novel genomes, revealing non-monophyletic patterns and genomic signatures associated with mitochondrial colonization.

Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut

This study uses single-cell transcriptomics to analyze Plasmodium falciparum development in the mosquito midgut, identifying transcriptional trajectories and stress responses, including genes encoding intrinsically disordered proteins.

Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets

This study uses single-cell RNA sequencing to analyze P. vivax-infected hepatocytes, identifying transcriptomic differences between schizonts and hypnozoites and potential therapeutic targets.

Sequence diversity and evolution of an iflavirus family associated with ticks

The paper identifies nine new iflavivirus genomes from ticks, finds incongruent viral and tick phylogenies, and detects strong positive selection in viral evolution.

Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and potential mechanisms for liver-stage differentiation.

This study characterizes the transcriptome and histone epigenome of Plasmodium vivax sporozoites, revealing transcriptional and post-transcriptional control mechanisms and potential pathways for hypnozoite formation.