Differential levels of IFNα subtypes in autoimmunity and viral infection
V. Bondet, M. P. Rodero, C. Posseme, P. Bost, J. Decalf, L. Haljasmagi, N. Bekaddour, G. Rice, V. Upasani, J.-P. Herbeuval, J. A. Reynolds, T. A. Briggs, I. N. Bruce, C. Mauri, D. Isenberg, , D. Duffy
The paper develops an ultrasensitive ELISA for IFN2 and applies it to study IFN subtype responses in viral infection and autoimmunity, revealing distinct protein ratios and potential auto-antibody effects.
bioRxiv · Mar 4, 2021 · PreprintImmunology