Cross-seeding Controls Aβ Fibril Populations and Resulting Function
H. S. Pan, M. J. Lucas, E. J. Verbeke, G. M. Partipilo, E. C. Helfman, L. Kann, B. K. Keitz, D. W. Taylor, L. J. Webb
This study investigates how cross-seeding of amyloid-beta peptides affects fibril structure and toxicity, showing that mutant seeds influence both structure and cytotoxicity in WT peptides.
bioRxiv · Oct 14, 2021Biochemistry