Author

L. Khellaf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Sarrazin· 1 shared A. Turtoi· 1 shared A. Zavoriti· 1 shared C. Barrachina· 1 shared C. Graber· 1 shared C. Honda· 1 shared D. Pourquier· 1 shared E. Fabbrizio· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Sarrazin

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Author profile →

2 papers

Recent·Most cited

Cancer-associated Fibroblast Spatial Heterogeneity and EMILIN1 Expression in Cancer Stroma Modulate TGF-beta Activity and CD8+ T-Cell Infiltration in Breast Cancer

C. Honda, S. Kurozumi, T. Fujii, D. Pourquier, L. Khellaf, F. Boissiere, J. Horiguchi, T. Oyama, K. Shirabe, J. Colinge, T. Yokobori, A. Turtoi

This study identifies EMILIN1 as a TGF-beta inhibitor expressed in IFN-gamma CAFs that modulates TGF-beta activity and CD8+ T-cell infiltration in breast cancer.

bioRxiv · Sep 12, 2023 · PreprintCancer Biology

The mouse HP1 proteins are essential for preventing liver tumorigenesis

N. Saksouk, S. Hajdari, M. Pratlong, C. Barrachina, C. Graber, A. Zavoriti, A. Sarrazin, N. Pirot, J.-Y. Noël, L. Khellaf, E. Fabbrizio, E. Julien, F. M. Cammas

This study shows that HP1 proteins prevent liver tumors in mice by maintaining chromatin structure and gene expression, and by suppressing retroviral activity.

bioRxiv · Apr 1, 2019Cancer Biology