Author

L. Lap

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. F. M. Dost· 1 shared A. Sexton-Oates· 1 shared A.-M. Dingemans· 1 shared C. Voegele· 1 shared E. J. Speel· 1 shared G. D. Valk· 1 shared H. Begthel· 1 shared H. Clevers· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. F. M. Dost

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1 paper

Recent·Most cited

Druggable Growth Dependencies and Tumor Evolution Analysis in Patient-Derived Organoids of Neuroendocrine Cancer

T. L. Dayton, N. Alcala, L. Moonen, L. den Hartigh, L. Mangiante, L. Lap, A. F. M. Dost, J. Beumer, S. Levy, R. S. van Leeuwaarde, W. M. Hackeng, K. Samsom, C. Voegele, A. Sexton-Oates, H. Begthel, , H. Clevers

This study establishes patient-derived tumor organoids (PDTOs) for neuroendocrine cancers, identifies therapeutic vulnerabilities, and highlights EGF dependency in pulmonary neuroendocrine tumors.

bioRxiv · Oct 31, 2022Cancer Biology