Author

L. Legrand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

O. BOUCHEZ· 3 shared A. GUIDOT· 2 shared C. Lopez-Roques· 2 shared R. Gopalan-Nair· 2 shared S. Genin· 2 shared A. Chenal· 1 shared A. Coissac· 1 shared A. Givaudan· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersEvolutionary Biology

O. BOUCHEZ

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genome sequences of equine influenza A subtype H3N8 viruses by long read sequencing and functional characterization of the PB1-F2 virulence factor of A/equine/Paris/1/2018

L. Kleij, E. Bruder, D. Raoux-Barbot, N. Lejal, Q. Nevers, C. Deloisy, B. Da Costa, L. Legrand, E. Barrey, A. Chenal, S. Pronost, B. Delmas, S. Dhorne-Pollet

This study uses long-read sequencing to characterize equine influenza A H3N8 viruses, identifying antigenic drift and a virulence-enhancing PB1-F2 protein variant.

bioRxiv · Oct 25, 2023 · PreprintMicrobiology

Evidence for increased fitness of a plant pathogen conferred by epigenetic variation

R. Gopalan-Nair, A. Coissac, L. Legrand, C. Lopez-Roques, Y. Pecrix, C. Vandecasteele, O. BOUCHEZ, X. Barlet, A. Lanois, A. Givaudan, J. Brillard, S. Genin, A. GUIDOT

This study shows epigenetic variation, specifically DNA methylation, contributes to rapid adaptation of the plant pathogen Ralstonia solanacearum to host plants.

bioRxiv · Aug 16, 2023 · PreprintEvolutionary Biology

Transcriptomic profiling reveals host-specific evolutionary pathways promoting enhanced fitness in the broad host range pathogen Ralstonia pseudosolanacearum

R. GOPALAN-NAIR, M. F. JARDINAUD, L. LEGRAND, C. LOPEZ-ROQUES, O. BOUCHEZ, S. GENIN, A. GUIDOT

This study shows that transcriptomic changes, not genetic ones, drive host-specific adaptation in Ralstonia pseudosolanacearum, revealing two distinct gene expression patterns linked to host genotype.

bioRxiv · May 12, 2023 · PreprintEvolutionary Biology

Identification of the first oomycete mating-type locus sequence in the grapevine downy mildew pathogen, Plasmopara viticola

Y. Dussert, L. Legrand, I. D. Mazet, C. Couture, M.-C. Piron, R.-F. Serre, O. Bouchez, P. Mestre, S. L. Toffolatti, T. Giraud, F. Delmotte

The paper identifies the mating-type locus in Plasmopara viticola, revealing a unique heterozygosity asymmetry and implications for pathogen evolution and management.

bioRxiv · Feb 26, 2020Evolutionary Biology