Author

B. Da Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

B. Delmas· 2 shared N. Lejal· 2 shared R. Le Goffic· 2 shared A. Chenal· 1 shared A. Dogliani· 1 shared A. Donchet· 1 shared A. Fraysse· 1 shared A. Huckriede· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

B. Delmas

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Genome sequences of equine influenza A subtype H3N8 viruses by long read sequencing and functional characterization of the PB1-F2 virulence factor of A/equine/Paris/1/2018

L. Kleij, E. Bruder, D. Raoux-Barbot, N. Lejal, Q. Nevers, C. Deloisy, B. Da Costa, L. Legrand, E. Barrey, A. Chenal, S. Pronost, B. Delmas, S. Dhorne-Pollet

This study uses long-read sequencing to characterize equine influenza A H3N8 viruses, identifying antigenic drift and a virulence-enhancing PB1-F2 protein variant.

bioRxiv · Oct 25, 2023 · PreprintMicrobiology

Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals

S. Thebault, N. Lejal, A. Dogliani, A. Donchet, A. Urvoas, M. Valerio-Lepiniec, M. Lavie, C. Baronti, F. Touret, B. da Costa, C. Bourgon, A. Fraysse, A. Saint-Albin-Deliot, J. Morel, B. Klonjkowski, , B. Delmas

This paper identifies biosynthetic proteins (Reps) that bind the SARS-CoV-2 spike RBD and neutralize the virus, including variants, with high potency and stability.

bioRxiv · May 10, 2022Microbiology

Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder

V. Laghi, V. Rezelj, L. Boucontet, M. Fretaud, B. Da Costa, P. Boudinot, I. Salinas, G. Lutfalla, M. Vignuzzi, J.-P. Levraud

This study tests SARS-CoV-2 replication in zebrafish larvae, finding limited infection except in the swim bladder, which shows some viral RNA and nucleoprotein expression.

bioRxiv · Apr 8, 2021Microbiology

Low doses of radiation increase the immunosuppressive profile of lung macrophages during viral infection and pneumonia

L. Meziani, C. Robert, M. Classe, B. Da Costa, M. Mondini, C. Clemenson, P. Mordant, S. Ammari, R. Le Goffic, E. Deutsch

This study shows low-dose radiation reduces lung inflammation by increasing IL-10 and decreasing IFN-gamma and IL-6 in macrophages during pneumonia and viral infection.

bioRxiv · May 11, 2020Immunology

Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo

O. Kocabiyik, V. Cagno, P. Jacob Silva, Y. Zhu, L. Sedano, Y. Bhide, J. Mettier, C. Medaglia, B. Da Costa, S. Constant, S. Huang, L. Kaiser, W. Hinrichs, A. Huckriede, R. Le Goffic, , F. Stellacci

The paper develops non-toxic virucidal macromolecules effective against multiple influenza strains in vitro and in vivo.

bioRxiv · Mar 18, 2020Microbiology