Monoallelic antigen expression in trypanosomes requires a stage-specific transcription activator
L. Lopez Escobar, B. Hanisch, C. Halliday, S. Dean, J. Sunter, R. J. Wheeler, K. Gull
The paper identifies ESB1 as a stage-specific activator required for monoallelic VSG transcription in Trypanosoma brucei, revealing its role in Pol I recruitment to the expression site body.
bioRxiv · May 6, 2021 · PreprintMicrobiology