The ATP-bound State of the Uncoupling Protein 1 (UCP1) from Molecular Simulations
L. Jacobsen, L. Lydersen, H. Khandelia
This study uses molecular dynamics simulations to generate the ATP-bound conformation of UCP1 and proposes mechanisms for ATP-mediated inhibition of proton leak.
bioRxiv · Mar 17, 2023Biophysics