Author

L. Mada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Perina· 2 shared R. Jorda· 2 shared A. M. Tumilovich· 1 shared A. R. Mekhtiev· 1 shared A. S. Rudovich· 1 shared A. V. Krech· 1 shared D. Kurfurstova· 1 shared E. Frank· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

M. Perina

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Author profile →

2 papers

Recent·Most cited

A-ring-fused pyrazoles of dihydrotestosterone targeting prostate cancer cells via the downregulation of the androgen receptor

M. Perina, M. A. Kiss, G. Motyan, E. Szczyrbova, M. Elias, V. Student, D. Kurfurstova, M. Kovalova, L. Mada, J. Bouchal, E. Frank, R. Jorda

This paper synthesizes and evaluates A-ring-fused pyrazoles derived from dihydrotestosterone as AR antagonists with antiproliferative activity in prostate cancer cells.

bioRxiv · Dec 17, 2022Pharmacology & Toxicology

Synthesis and Biological Evaluation of New Isoxazolyl Steroids as Anti-Prostate Cancer Agents

A. S. Rudovich, M. Perina, A. V. Krech, M. Y. Novozhilova, A. M. Tumilovich, T. V. Shkel, I. P. Grabovec, M. Kvasnica, L. Mada, M. G. Zavialova, A. R. Mekhtiev, R. Jorda, V. N. Zhabinskii, V. A. Khripach

The paper synthesizes new isoxazolyl steroids and evaluates their anti-prostate cancer activity by testing their effects on androgen receptor signaling and CYP17A1 enzyme activity.

bioRxiv · Oct 28, 2022Pharmacology & Toxicology