Pharmacology & ToxicologybioRxiv
A-ring-fused pyrazoles of dihydrotestosterone targeting prostate cancer cells via the downregulation of the androgen receptor
M. Perina, M. A. Kiss, G. Motyan…·R. Jorda
This paper synthesizes and evaluates A-ring-fused pyrazoles derived from dihydrotestosterone as AR antagonists with antiproliferative activity in prostate cancer cells.
DOI 10.1016/j.ejmech.2023.115086