Author

L. Modolo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:chicken / avian· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Picard· 3 shared A. Moussy· 2 shared C. Fourneaux· 2 shared E. Vallin· 2 shared O. Gandrillon· 2 shared S. Gonin-Giraud· 2 shared A. Bonnaffoux· 1 shared A. J. M. Larsson· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

F. Picard

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Differentiation is accompanied by a progressive loss in transcriptional memory

C. Fourneaux, L. Racine, C. Koering, S. Dussurgey, E. Vallin, A. Moussy, R. Parmentier, F. Brunard, D. Stockholm, L. Modolo, F. Picard, O. Gandrillon, A. Paldi, S. Gonin-Giraud

The paper quantifies how transcriptional memory decreases during differentiation by comparing related and unrelated cells across generations.

bioRxiv · Nov 2, 2022Cell Biology

Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase

L. Colin, C. Reyes, J. Berthezene, L. Maestroni, L. Modolo, E. Toselli, N. Chanard, S. Schaak, O. Cuvier, Y. Gachet, S. Coulon, P. Bernard, S. Tournier

This study shows that condensin, positioned at telomeres by shelterin proteins, drives sister-telomere disjunction in anaphase through a telomere-specific mechanism.

bioRxiv · Mar 18, 2022Cell Biology

Evidence for close molecular proximity between reverting and undifferentiated cells

S. Zreika, C. Fourneaux, E. Vallin, L. Modolo, R. Seraphin, A. Moussy, E. Ventre, M. Bouvier, A. Ozier-Lafontaine, A. Bonnaffoux, F. Picard, O. Gandrillon, S. Gonin-Giraud

The paper characterizes reverting cells by comparing their molecular state to undifferentiated cells using single-cell transcriptomic data and finds they return to an earlier molecular state with minimal differences.

bioRxiv · Feb 1, 2022Cell Biology

Clonally distinct differentiation trajectories shape CD8+ memory T cell heterogeneity after acute viral infections in humans

J. E. Mold, L. Modolo, J. Hard, M. Zamboni, A. J. M. Larsson, C.-J. Eriksson, P. Stahl, E. Borgstrom, S. Picelli, B. Reinius, R. Sandberg, P. Reu, C. Talavera-Lopez, B. Andersson, K. Blom, , J. Frisen

The paper tracks CD8+ T cell clones after yellow fever vaccination, showing clonal selection and biased differentiation trajectories shaping memory T cell heterogeneity.

bioRxiv · Nov 8, 2019 · PreprintImmunology