L. Moretto

New paradigms in actomyosin energy transduction: critical evaluation of non-traditional models for orthophosphate release

The paper evaluates alternative models for Pi-release timing relative to the power-stroke in actomyosin energy transduction and proposes critical tests for a unified understanding.

Optimized single molecule fluorescence sheds light on elusive enzymatic mechanisms

The paper uses optimized single molecule fluorescence to study ATP turnover mechanisms in myosin and actomyosin, revealing multiple exponential processes and non-specific ATP binding.