Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins
A. Lublin, C. Katz, N. Gruzdev, I. Yadid, I. Bloch, Y. Farnoushi, L. Simanov, A. Berkovitz, D. Elyahu, J. Pitcovski, E. Shahar
This paper develops an oral vaccine using E. coli expressing LTB-fused IBV proteins that induces strong immune responses and reduces viral shedding in chickens.
bioRxiv · Oct 4, 2021Immunology