CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan
L. Heilg, F. Natasha, N. Trinks, V. K. AIMANIANDA BOPAIAH, S. Sze Wah Wong, T. Fontaine, U. Terpitz, L. Strobel, F. Le Mauff, D. Sheppard, S. Schaeuble, O. Kurzai, K. Huenniger, E. Weiss, M. Vargas, , J. Loeffler
This study identifies galactosaminogalactan as the fungal ligand for CD56 on human NK cells, triggering antifungal responses and immune cell activation.
bioRxiv · Aug 18, 2023 · PreprintMicrobiology