Author

O. Kurzai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:C. elegans· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. Panagiotou· 2 shared A. Aldejohann· 1 shared A. E. Barber· 1 shared A. M. Aldejohann· 1 shared B. Hube· 1 shared C. Sponholz· 1 shared D. Sheppard· 1 shared D. Thomas-Rüddel· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersMicrobiology

G. Panagiotou

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan

L. Heilg, F. Natasha, N. Trinks, V. K. AIMANIANDA BOPAIAH, S. Sze Wah Wong, T. Fontaine, U. Terpitz, L. Strobel, F. Le Mauff, D. Sheppard, S. Schaeuble, O. Kurzai, K. Huenniger, E. Weiss, M. Vargas, , J. Loeffler

This study identifies galactosaminogalactan as the fungal ligand for CD56 on human NK cells, triggering antifungal responses and immune cell activation.

bioRxiv · Aug 18, 2023 · PreprintMicrobiology

The sphingolipid inhibitor myriocin increases susceptibility of Candida auris to amphotericin B

H. Stieber, L. Junghanns, H. Wilhelm, M. Batliner, A. M. Aldejohann, O. Kurzai, R. Martin

This study shows that myriocin, a sphingolipid inhibitor, increases susceptibility of Candida auris to amphotericin B and anidulafungin, suggesting sphingolipids as a target for overcoming resistance.

bioRxiv · Apr 14, 2022Microbiology

Transient mitochondria dysfunction confers fungal cross-resistance between macrophages and fluconazole

S. Siscar-Lewin, T. Gabaldon, A. Aldejohann, O. Kurzai, B. Hube, S. Brunke

This study shows that C. glabrata's mitochondrial dysfunction confers cross-resistance to antifungals and macrophages, suggesting a bet-hedging strategy.

bioRxiv · Jan 14, 2021Evolutionary Biology

Ex vivo Immune Profiling in Patient Blood enables Quantification of innate immune Effector Functions

T. Lehnert, I. Leonhardt, S. Timme, D. Thomas-Rüddel, F. Bloos, C. Sponholz, O. Kurzai, M. T. Figge, K. Hünniger

The paper quantifies innate immune effector functions in patient blood after ex vivo infection, revealing altered immune responses post-cardiac surgery.

bioRxiv · Oct 1, 2020Immunology

Effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure

A. E. Barber, J. Riedel, T. Sae-Ong, K. Kang, W. Brabetz, G. Panagiotou, H. B. Deising, O. Kurzai

This study examines the effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure, finding low resistance rates and no significant genomic impact.

bioRxiv · May 26, 2020Microbiology