Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition
J. Azadmanesh, K. Slobodnik, L. Struble, W. E. Lutz, L. Coates, K. L. Weiss, D. A. A. Myles, T. Kroll, G. E. Borgstahl
The paper investigates the mechanism of product inhibition in human MnSOD by combining neutron diffraction and X-ray absorption spectroscopy to determine the atomic and electronic structures of the enzyme in different states.
bioRxiv · Jan 26, 2024Biochemistry