Author

L. Temme

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. I. Wells· 1 shared C. R. M. Asquith· 1 shared D. H. Drewry· 1 shared F. E. Kwarcinski· 1 shared G. J. Tizzard· 1 shared J. Pickett· 1 shared P. Sinha· 1 shared R. Zutshi· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

C. I. Wells

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1 paper

Recent·Most cited

Identification and Optimization of cell active 4-anilino-quin(az)oline Inhibitors for Protein Kinase Novel 3 (PKN3)

C. R. M. Asquith, L. Temme, T. Laitinen, J. Pickett, F. E. Kwarcinski, P. Sinha, C. I. Wells, G. J. Tizzard, R. Zutshi, D. H. Drewry

The paper identifies 7-iodo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine as a potent PKN3 inhibitor with an IC50 of 1.3 μM in cells, suggesting its potential as a tool for studying PKN3 biology and therapeutic applications.

bioRxiv · Mar 2, 2020 · PreprintPharmacology & Toxicology