ATAD1 and the integrated stress response prevent clogging of TOM and damage caused by un-imported mitochondrial proteins
J. Kim, M. Goldstein, L. Zecchel, H. Weidberg
This study shows that ATAD1 and the integrated stress response prevent mitochondrial clogging and damage from un-imported proteins by removing stalled proteins and reducing translation.
bioRxiv · Sep 6, 2023Cell Biology