Lethal Sudan virus infection in IFNAR-/- mice reveals hallmarks of a cytokine storm
Michelle Gellhorn Serra, Cornelius Rohde, Lucie Sauerhering, Lars Meier, Lennart Kämper, Pauline Neubecker, Markus Eickmann, Alexandra Kupke, Stephan Becker, Anke Werner
This study shows that SUDV infection in IFNAR-/- mice leads to systemic viral spread and a cytokine storm, supporting their use as a model for filovirus research.
bioRxiv · Mar 31, 2026 · PreprintMicrobiology